{"id":15057,"date":"2021-06-16T14:05:00","date_gmt":"2021-06-16T13:05:00","guid":{"rendered":"https:\/\/saera.eu\/en\/?p=15057"},"modified":"2025-03-03T14:06:01","modified_gmt":"2025-03-03T14:06:01","slug":"report-on-prasad-et-al-2021-brain-disease-network-analysis-to-elucidate-the-neurological-manifestations-of-covid-19","status":"publish","type":"post","link":"https:\/\/saera.eu\/en\/2021\/06\/16\/report-on-prasad-et-al-2021-brain-disease-network-analysis-to-elucidate-the-neurological-manifestations-of-covid-19\/","title":{"rendered":"Report on Prasad et al. (2021), Brain Disease Network Analysis to Elucidate the Neurological Manifestations of COVID-19"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"15057\" class=\"elementor elementor-15057\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-122dae94 e-flex e-con-boxed e-con e-parent\" data-id=\"122dae94\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-622ea7a3 e-con-full e-flex e-con e-child\" data-id=\"622ea7a3\" data-element_type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-4aeb0a06 e-flex e-con-boxed e-con e-child\" data-id=\"4aeb0a06\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-68320cd4 elementor-widget elementor-widget-text-editor\" data-id=\"68320cd4\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<h2 class=\"page-title\"><span style=\"color: #000666;\">Report on Prasad et al. (2021), Brain Disease Network Analysis to Elucidate the Neurological Manifestations of COVID-19<\/span><\/h2>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5b34c455 elementor-align-right elementor-widget elementor-widget-post-info\" data-id=\"5b34c455\" data-element_type=\"widget\" data-widget_type=\"post-info.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<link rel=\"stylesheet\" href=\"https:\/\/saera.eu\/en\/wp-content\/plugins\/elementor\/assets\/css\/widget-icon-list.min.css\"><link rel=\"stylesheet\" href=\"https:\/\/saera.eu\/en\/wp-content\/plugins\/pro-elements\/assets\/css\/widget-theme-elements.min.css?ver=1747297119\">\t\t<ul class=\"elementor-inline-items elementor-icon-list-items elementor-post-info\">\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-0d080fc elementor-inline-item\" itemprop=\"datePublished\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-calendar\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M12 192h424c6.6 0 12 5.4 12 12v260c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V204c0-6.6 5.4-12 12-12zm436-44v-36c0-26.5-21.5-48-48-48h-48V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H160V12c0-6.6-5.4-12-12-12h-40c-6.6 0-12 5.4-12 12v52H48C21.5 64 0 85.5 0 112v36c0 6.6 5.4 12 12 12h424c6.6 0 12-5.4 12-12z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-date\">\n\t\t\t\t\t\t\t\t\t\t<time>16\/06\/2021<\/time>\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<li class=\"elementor-icon-list-item elementor-repeater-item-e2c89b4 elementor-inline-item\" itemprop=\"about\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-tags\" viewBox=\"0 0 640 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M497.941 225.941L286.059 14.059A48 48 0 0 0 252.118 0H48C21.49 0 0 21.49 0 48v204.118a48 48 0 0 0 14.059 33.941l211.882 211.882c18.744 18.745 49.136 18.746 67.882 0l204.118-204.118c18.745-18.745 18.745-49.137 0-67.882zM112 160c-26.51 0-48-21.49-48-48s21.49-48 48-48 48 21.49 48 48-21.49 48-48 48zm513.941 133.823L421.823 497.941c-18.745 18.745-49.137 18.745-67.882 0l-.36-.36L527.64 323.522c16.999-16.999 26.36-39.6 26.36-63.64s-9.362-46.641-26.36-63.64L331.397 0h48.721a48 48 0 0 1 33.941 14.059l211.882 211.882c18.745 18.745 18.745 49.137 0 67.882z\"><\/path><\/svg>\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text elementor-post-info__item elementor-post-info__item--type-terms\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-post-info__terms-list\">\n\t\t\t\t<a href=\"https:\/\/saera.eu\/en\/tag\/covid-19\/\" class=\"elementor-post-info__terms-list-item\">COVID-19<\/a>, <a href=\"https:\/\/saera.eu\/en\/tag\/neuroscience\/\" class=\"elementor-post-info__terms-list-item\">Neuroscience<\/a>\t\t\t\t<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4a04884d elementor-widget elementor-widget-text-editor\" data-id=\"4a04884d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3><!-- wp:paragraph {\"align\":\"right\"} --><\/h3>\n<p style=\"text-align: right;\">By Francia De Los Reyes MD and Master in Applied <a href=\"https:\/\/www.saera.eu\/en\/applied-neuroscience-programmes\/\">Neuroscience<\/a> student<\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph --><\/p>\n<p><!-- \/wp:paragraph --><!-- wp:paragraph --><\/p>\n<p>The twenty-first century has brought massive and sweeping changes in the field of neuroscience and the specializations that are under it. One of the most important concepts that have been established is how gene expression in the human neuron is altered by the physiologic and pathologic conditions that the human body is subjected to. The concept of gene expression dictating the cellular mechanisms is, in essence, genotype coding for the phenotype. This is true for pluripotent stem cells as much as it is true for cells that are in the terminal configuration and no longer undergo the cell cycle.<\/p>\n<p>One of the timeliest applications for the role of changes in gene expression and its role in functional and structural changes in the brain is how the presence of certain proteins are more abundant in patients with neurologic manifestation of COVID-19 versus in normal controls. The work of Prasad et al. (2021) showed how certain proteins that are specific to the brain can develop protein-protein interaction with an identified 332 human genes and the other genes in their interaction network. This study gained insight from the work of Gordon, et al. (2020) which provided an interaction map for proteins that are involved in COVID-19 symptomatology to investigate drug repurposing for treatment.<\/p>\n<p>The concept of brain-specific protein-protein interaction allowed for the establishment of the project that establishes the network for COVID-19 target genes. The project utilized the TissueNet v.2 database that generated 165,240 interactions. The TissueNet provided RNA-Seq and protein-based assay information that has been taken from the genotype-tissue expression project (GTEX) and correlated with the human protein atlas (HPA). Although certain protein-protein interactions are only at the theoretical, several experimentally validated protein interaction information were provided and this was compared with the 332 genes of humans that were documented to have COVID-19 interaction.<\/p>\n<p>It is important to emphasize that identified genes may be in existence in the human brain in normal conditions and an increase or a decrease in their expression may be indicative of or contributory to the manifestation of the pathology. In this regard, other structures in the peripheral nervous system or outside of the nervous system may also express these genes but in a much more regulated manner or they may be expressed normally at a particular level in tissues outside of the human nervous system but the expression in the nervous system may indicate a disease-condition.<\/p>\n<p>Furthermore, identification of the genes and their neighboring interaction, the protein-to-protein interaction that such relationships establish, and whether or not one part of the pair in the interaction or both are expressed aberrantly, serve the larger purpose of identifying existing brain-related disorders that have been reported in the past to harbor the combination of gene interaction.<\/p>\n<p>For the research of Prasad et al. (2021) the Gene ORGANizer database was used and such database utilized the curated datasets from DisGeNET and human phenotype ontology (HPO). Evaluation of the specific disease-gene interaction was necessary to confirm the interaction that was established using the datasets. There were 2002 disease-gene interactions that were specific to the brain and these had 127 identifiable brain disorders. However, in the 2002 disease-gene interaction, only 653 genes were considered as valid for investigation for the 127 brain disorders. Among the 653 genes, 43 were the direct target of COVID-19. To specifically detect importance of the interactions, the COVID-19 target genes were divided into interaction and nearest neighbor groups, and labeled as modules. The modules have a specific pathway of involvement and these have a functional impact on the manifestation of COVID-19 as well as other diseases that it may be related to.<\/p>\n<p>The modules underwent further analysis in terms of function and it was shown that Module-1 contributes to RNA splicing, mRNA processing, protein complex biogenesis and assembly. Moreover, the study of the regulatory elements and pathways related to apoptosis showed the role of Module-1 in proteolysis, ribosome pathway, spliceosome pathway, in Huntington\u2019s disease pathway, and cancer pathways. Other conditions that were identified in the evaluation includes ataxia, dysarthria, spasticity, encephalopathy, coma, and delayed speech and language development among others.<\/p>\n<p>In comparison, the analysis of Module-2 showed that the genes contribute to macromolecular complex assembly, negative regulation of gene expression, RNA transport, and localization. Moreover, they also have a contribution in spliceosome, ribosome, cell cycle, gliomas, pathways in cancer, and RIG-I like receptor signaling pathways. In terms of disease-condition, they have been documented in hydrocephalus, dementia, autism, muscular dystrophy, language impairment, and frontotemporal dementia.<\/p>\n<p>Module-3, on the other hand, also contain genes that have a role in RNA splicing, cell division, mRNA processing, spindle assembly, and nuclear division-related biological process. In terms of their pathway interaction, the module has a role in Notch signaling pathways, Toll-like receptor signaling pathways, and SNARE interaction in vesicular transport. The genes in this module have been reported in ataxia, sleep apnea, leukodystrophy, cerebral ataxia, and Joubert syndrome.<\/p>\n<p>Interestingly, although some functions, pathways, and diseases overlap, the modules have specific conditions to themselves. In the case of Module-4, the involved function includes RNA processing, translational elongation, ncRNA processing, and in the viral infection cycle. The role in the viral infection cycle is much more contributory in terms of viruses triggering specific gene expression response. The pathways that they are involved in includes NOD-like receptor signaling pathways, Parkinson\u2019s disease, Huntington\u2019s disease, and Cytosolic DNA sensing pathways. Ataxia, spasticity, amyotrophic lateral sclerosis, chorea, and auditory neuropathy are among the diseases where the genes in the module have been reported.<\/p>\n<p>Lastly, Module-5 showed that it plays a role in the regulation of transcription from RNA polymerase II promoter, chromatin modification, regulation of transcription, and in cellular protein catabolic process. \u00a0In terms of the pathways, it has shown involvement in the Wnt signaling pathways, viral reproduction, MAPK signaling pathway, neurotrophin signaling pathway, TGF-beta signaling pathway, and ErbB signaling pathway. Disease-conditions such as ataxia, myopathy, Chiari malformation, GAIT ataxia, limb ataxia, and febrile seizures have reported the presence of the genes in this module.<\/p>\n<p>The research reports that early SARS-CoV-2 infection involved these modules such that the virus hijacks the cellular and extracellular interaction where these modules are involved in and utilize the genes for its own RNA synthesis. It may be hypothesized that, because the genes are associated with ataxia, spasticity, encephalopathy, and dementia, the patients who contract COVID-19 may have a higher risk of manifesting these clinical conditions. However, it must be emphasized that association is not correlation and that putative correlation is not necessarily causation.<\/p>\n<p>The purpose of identifying gene expression and protein-protein interaction with their associated clinical manifestations is to enable drug repurposing for targeted treatment and to hamper the cytopathic changes caused by the virus and the immune response of the human body that is due to the presence of the virus. Evaluation of potential targets showed that FDA approved drugs, fulvestrant, tamoxifen, raloxifene, estradiol, ethinylestradiol may have potential for targeting the ESR1 gene, which is one of the five key genes that were identified as useable for drug repurposing. TP53 is also one of the five genes that were identified and the drugs that were candidates for repurposing to target this gene included anti-cancer drugs. Moreover, MYC gene was also detected and showed interaction with imatinib which is tyrosine-kinase inhibitor. The identified gene HSP90AA1 showed interaction with rifabutin, which is an antimicrobial drug for Mycobacterium avium-intracellulare.<\/p>\n<p>The difficulty with utilizing the identified genes to determine the drugs for repurposing is not necessarily on whether the existing medications may genuinely work. The problem in this situation is deploying further studies to determine its efficacy based on empirical evidence and this has to be done at the level of the tissue culture that contains the SARS-CoV-2 virus. Future hurdles into the use of the identified drugs include animal testing to determine actual in-vivo performance and to have an idea on the effective dose based on in-vivo testing. Evaluation of the organs of those that underwent animal testing should be done using microscopy to establish a phenotype of the injury and to determine the effects of the repurposed drug visually as cellular changes pertaining to disease involvement. Animal testing may also be used as an early indicator of the effective dose that did not appear to have significant adverse effect to the animals who received the treatment. However, the adverse event should not be limited to documenting the number of animals who because of the drug. It is equally important to evaluate whether the internal organs of the animal subjects show inflammatory response, viremia, or drug- related toxicity that manifested as multi-organ failure. Success in the laboratory testing and animal testing may push the drug being repurposed to the actual phases of human clinical trials to determine how much the conceptual analysis will translate to an effective drug-repurposing protocol.<\/p>\n<p>The role of gene expression in determining disease phenotype and finding the appropriate drug to treat the condition may be severely circuitous and may not necessarily lead to a functional treatment protocol. However, much of the options that can be provided for in the future, may it be related to COVID-19 treatment or other diseases, would not have been possible without the contribution of the exhaustive analytical processes that allowed establishing the interaction of genes and diseases to find a clinically significant solution.<\/p>\n<p><!-- \/wp:paragraph --><!-- wp:shortcode --><\/p>\n<p><!-- \/wp:shortcode --><!-- wp:paragraph --><\/p>\n<p><!-- \/wp:paragraph --><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2742d255 elementor-widget elementor-widget-toggle\" data-id=\"2742d255\" data-element_type=\"widget\" data-widget_type=\"toggle.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-toggle{text-align:start}.elementor-toggle .elementor-tab-title{font-weight:700;line-height:1;margin:0;padding:15px;border-bottom:1px solid #d5d8dc;cursor:pointer;outline:none}.elementor-toggle .elementor-tab-title .elementor-toggle-icon{display:inline-block;width:1em}.elementor-toggle .elementor-tab-title .elementor-toggle-icon svg{margin-inline-start:-5px;width:1em;height:1em}.elementor-toggle .elementor-tab-title .elementor-toggle-icon.elementor-toggle-icon-right{float:right;text-align:right}.elementor-toggle .elementor-tab-title .elementor-toggle-icon.elementor-toggle-icon-left{float:left;text-align:left}.elementor-toggle .elementor-tab-title .elementor-toggle-icon .elementor-toggle-icon-closed{display:block}.elementor-toggle .elementor-tab-title .elementor-toggle-icon .elementor-toggle-icon-opened{display:none}.elementor-toggle .elementor-tab-title.elementor-active{border-bottom:none}.elementor-toggle .elementor-tab-title.elementor-active .elementor-toggle-icon-closed{display:none}.elementor-toggle .elementor-tab-title.elementor-active .elementor-toggle-icon-opened{display:block}.elementor-toggle .elementor-tab-content{padding:15px;border-bottom:1px solid #d5d8dc;display:none}@media (max-width:767px){.elementor-toggle .elementor-tab-title{padding:12px}.elementor-toggle .elementor-tab-content{padding:12px 10px}}.e-con-inner>.elementor-widget-toggle,.e-con>.elementor-widget-toggle{width:var(--container-widget-width);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-toggle\">\n\t\t\t\t\t\t\t<div class=\"elementor-toggle-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-6581\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-6581\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon elementor-toggle-icon-left\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-closed\"><svg class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-toggle-icon-opened\"><svg class=\"elementor-toggle-icon-opened e-font-icon-svg e-fas-caret-up\" viewBox=\"0 0 320 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M288.662 352H31.338c-17.818 0-26.741-21.543-14.142-34.142l128.662-128.662c7.81-7.81 20.474-7.81 28.284 0l128.662 128.662c12.6 12.599 3.676 34.142-14.142 34.142z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-toggle-title\" tabindex=\"0\">References<\/a>\n\t\t\t\t\t<\/div>\n\n\t\t\t\t\t<div id=\"elementor-tab-content-6581\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-6581\"><ol>\n<li>Prasad, K., AlOmar, S. Y., Alqahtani, S., Malik, M. Z., &amp; Kumar, V. (2021). Brain Disease Network Analysis to Elucidate the Neurological Manifestations of COVID-19.&nbsp;<em>Molecular&nbsp;<\/em><a href=\"https:\/\/www.saera.eu\/en\/applied-neuroscience-programmes\/\" target=\"_blank\"><i>neurobiology<\/i><\/a>,&nbsp;<em>58<\/em>(5), 1875\u20131893.&nbsp;<a href=\"https:\/\/doi.org\/10.1007\/s12035-020-02266-w\">https:\/\/doi.org\/10.1007\/s12035-020-02266-w<\/a><\/li>\n<li>Gordon, D. E., Jang, G. M., Bouhaddou, M., Xu, J., Obernier, K., White, K. M., O\u2019Meara, M. J., Rezelj, V. V., Guo, J. Z., Swaney, D. L., Tummino, T. A., H\u00fcttenhain, R., Kaake, R. M., Richards, A. L., Tutuncuoglu, B., Foussard, H., Batra, J., Haas, K., Modak, M., Kim, M., \u2026 Krogan, N. J. (2020). A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.&nbsp;<em>Nature<\/em>,&nbsp;<em>583<\/em>(7816), 459\u2013468.&nbsp;<a href=\"https:\/\/doi.org\/10.1038\/s41586-020-2286-9\">https:\/\/doi.org\/10.1038\/s41586-020-2286-9<\/a><\/li>\n<\/ol><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-4f02db01 e-con-full e-flex e-con e-child\" data-id=\"4f02db01\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-75f6b0fb elementor-widget elementor-widget-spacer\" data-id=\"75f6b0fb\" data-element_type=\"widget\" data-widget_type=\"spacer.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-column 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.elementor-widget-empty-icon,.e-con>.elementor-widget-spacer.elementor-widget-empty .elementor-widget-empty-icon{position:absolute;top:0;bottom:0;left:0;right:0;margin:auto;padding:0;width:22px;height:22px}<\/style>\t\t<div class=\"elementor-spacer\">\n\t\t\t<div class=\"elementor-spacer-inner\"><\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6d9241bd elementor-widget elementor-widget-wp-widget-text\" data-id=\"6d9241bd\" data-element_type=\"widget\" data-widget_type=\"wp-widget-text.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5>Check our educational programmes:<\/h5>\t\t\t<div class=\"textwidget\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1c563f35 e-grid e-con-boxed e-con e-child\" data-id=\"1c563f35\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1a3e808d elementor-position-top elementor-widget elementor-widget-image-box\" data-id=\"1a3e808d\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.22.0 - 26-06-2024 *\/\n.elementor-widget-image-box .elementor-image-box-content{width:100%}@media (min-width:768px){.elementor-widget-image-box.elementor-position-left .elementor-image-box-wrapper,.elementor-widget-image-box.elementor-position-right .elementor-image-box-wrapper{display:flex}.elementor-widget-image-box.elementor-position-right .elementor-image-box-wrapper{text-align:end;flex-direction:row-reverse}.elementor-widget-image-box.elementor-position-left .elementor-image-box-wrapper{text-align:start;flex-direction:row}.elementor-widget-image-box.elementor-position-top .elementor-image-box-img{margin:auto}.elementor-widget-image-box.elementor-vertical-align-top .elementor-image-box-wrapper{align-items:flex-start}.elementor-widget-image-box.elementor-vertical-align-middle .elementor-image-box-wrapper{align-items:center}.elementor-widget-image-box.elementor-vertical-align-bottom .elementor-image-box-wrapper{align-items:flex-end}}@media (max-width:767px){.elementor-widget-image-box .elementor-image-box-img{margin-left:auto!important;margin-right:auto!important;margin-bottom:15px}}.elementor-widget-image-box .elementor-image-box-img{display:inline-block}.elementor-widget-image-box .elementor-image-box-title a{color:inherit}.elementor-widget-image-box .elementor-image-box-wrapper{text-align:center}.elementor-widget-image-box .elementor-image-box-description{margin:0}<\/style><div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><a href=\"https:\/\/www.saera.eu\/en\/audiology\/\" tabindex=\"-1\"><img fetchpriority=\"high\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/oreja_cuadrado-1-1-300x300.jpg\" class=\"attachment-medium size-medium wp-image-14634\" alt=\"\" srcset=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/oreja_cuadrado-1-1-300x300.jpg 300w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/oreja_cuadrado-1-1-150x150.jpg 150w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/oreja_cuadrado-1-1-120x120.jpg 120w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/oreja_cuadrado-1-1-220x220.jpg 220w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/oreja_cuadrado-1-1-390x390.jpg 390w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/oreja_cuadrado-1-1.jpg 500w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/figure><div class=\"elementor-image-box-content\"><h4 class=\"elementor-image-box-title\"><a href=\"https:\/\/www.saera.eu\/en\/audiology\/\">Audiology<\/a><\/h4><\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-463327cd elementor-position-top elementor-widget elementor-widget-image-box\" data-id=\"463327cd\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><a href=\"https:\/\/saera.eu\/en\/optometry\/\" tabindex=\"-1\"><img decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/ojo_cuadrado-1-1-300x300.jpg\" class=\"attachment-medium size-medium wp-image-14637\" alt=\"\" srcset=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/ojo_cuadrado-1-1-300x300.jpg 300w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/ojo_cuadrado-1-1-150x150.jpg 150w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/ojo_cuadrado-1-1-120x120.jpg 120w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/ojo_cuadrado-1-1-220x220.jpg 220w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/ojo_cuadrado-1-1-390x390.jpg 390w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/ojo_cuadrado-1-1.jpg 500w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/figure><div class=\"elementor-image-box-content\"><h4 class=\"elementor-image-box-title\"><a href=\"https:\/\/saera.eu\/en\/optometry\/\">Optometry<\/a><\/h4><\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-183f6feb elementor-position-top elementor-widget elementor-widget-image-box\" data-id=\"183f6feb\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><a href=\"https:\/\/saera.eu\/en\/applied-neuroscience-programmes\/\" tabindex=\"-1\"><img decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/cerebro_cuadrado-1-1-300x300.jpg\" class=\"attachment-medium size-medium wp-image-14636\" alt=\"\" srcset=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/cerebro_cuadrado-1-1-300x300.jpg 300w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/cerebro_cuadrado-1-1-150x150.jpg 150w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/cerebro_cuadrado-1-1-120x120.jpg 120w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/cerebro_cuadrado-1-1-220x220.jpg 220w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/cerebro_cuadrado-1-1-390x390.jpg 390w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/cerebro_cuadrado-1-1.jpg 500w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/figure><div class=\"elementor-image-box-content\"><h4 class=\"elementor-image-box-title\"><a href=\"https:\/\/saera.eu\/en\/applied-neuroscience-programmes\/\">Neuroscience<\/a><\/h4><\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-48565ae6 elementor-position-top elementor-widget elementor-widget-image-box\" data-id=\"48565ae6\" data-element_type=\"widget\" data-widget_type=\"image-box.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<div class=\"elementor-image-box-wrapper\"><figure class=\"elementor-image-box-img\"><a href=\"https:\/\/saera.eu\/en\/speech-and-language-therapy-programmes\/\" tabindex=\"-1\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"300\" src=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/Fonoaudiologia-1-1-300x300.jpg\" class=\"attachment-medium size-medium wp-image-14635\" alt=\"\" srcset=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/Fonoaudiologia-1-1-300x300.jpg 300w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/Fonoaudiologia-1-1-150x150.jpg 150w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/Fonoaudiologia-1-1-120x120.jpg 120w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/Fonoaudiologia-1-1-220x220.jpg 220w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/Fonoaudiologia-1-1-390x390.jpg 390w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2024\/06\/Fonoaudiologia-1-1.jpg 500w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/a><\/figure><div class=\"elementor-image-box-content\"><h4 class=\"elementor-image-box-title\"><a href=\"https:\/\/saera.eu\/en\/speech-and-language-therapy-programmes\/\">Speech-Language Pathology<\/a><\/h4><\/div><\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a9a6ba4 elementor-widget elementor-widget-wp-widget-text\" data-id=\"3a9a6ba4\" data-element_type=\"widget\" data-widget_type=\"wp-widget-text.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5>Search:<\/h5>\t\t\t<div class=\"textwidget\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-53fcc1e3 elementor-widget elementor-widget-wp-widget-search\" data-id=\"53fcc1e3\" data-element_type=\"widget\" data-widget_type=\"wp-widget-search.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<form role=\"search\" class=\"bs-search search-form\" method=\"get\" action=\"https:\/\/saera.eu\/en\/\">\n    <div class=\"search-wrap\">\n    \t<label class=\"screen-reader-text\">\n    \t\tSearch for:    \t<\/label>\n        <input type=\"search\" placeholder=\"Searching...\" name=\"s\" class=\"search-input\" value=\"\" \/>\n        <button type=\"submit\"  value=\"Search\"><i class=\"flaticon-search\"><\/i><\/button>\n    <\/div>\n<\/form>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-48a82c56 elementor-widget elementor-widget-wp-widget-text\" data-id=\"48a82c56\" data-element_type=\"widget\" data-widget_type=\"wp-widget-text.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5>Latest Posts<\/h5>\t\t\t<div class=\"textwidget\"><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-364d7251 elementor-widget elementor-widget-rsblog\" data-id=\"364d7251\" data-element_type=\"widget\" data-widget_type=\"rsblog.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t         \r\n\t\t<div class=\"rs-blog-grid rs-blog-grid2\">            \r\n\t\t\t\r\n            <div class=\"row blog-gird-item\">\r\n                \r\n\t\t\t \t\t\t\t\t\t\r\n\t\t\t\t\t<div class=\"grid-item col-lg-12  filter_audiology filter_blog filter_masters-thesis \">\r\n\r\n                                                    <div class=\"no-gutter blog-item rs-blog-grid1\">\r\n                                                           \r\n                                <div class=\"image-part\">\r\n                                    <a href=\"https:\/\/saera.eu\/en\/2026\/03\/17\/speech-in-noise-testing-in-arabic-a-literature-review-and-clinical-implications-for-lebanese-arabic\/\">\r\n                                        <img loading=\"lazy\" decoding=\"async\" width=\"1536\" height=\"1024\" src=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/03\/Mar-17-2026-10_09_50-AM.png\" class=\"attachment-full size-full wp-post-image\" alt=\"\" srcset=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/03\/Mar-17-2026-10_09_50-AM.png 1536w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/03\/Mar-17-2026-10_09_50-AM-300x200.png 300w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/03\/Mar-17-2026-10_09_50-AM-1024x683.png 1024w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/03\/Mar-17-2026-10_09_50-AM-768x512.png 768w\" sizes=\"(max-width: 1536px) 100vw, 1536px\" \/>                                    <\/a> \r\n                                <\/div>                             \r\n                                \r\n                                <div class=\"blog-content\">                                    \r\n                                                                               <ul class=\"blog-meta\">\r\n                                                                                                                                            <li><i class=\"fa fa-calendar-check-o\"><\/i> 17 March 2026<\/li>\r\n                                                                                                                                                                                <\/ul>\r\n                                                                                \r\n                                        <h3 class=\"title dd\"><a href=\"https:\/\/saera.eu\/en\/2026\/03\/17\/speech-in-noise-testing-in-arabic-a-literature-review-and-clinical-implications-for-lebanese-arabic\/\">Speech-in-Noise Testing in Arabic: A Literature Review and Clinical Implications for Lebanese Arabic<\/a><\/h3>\r\n                                                                                <div class=\"btn-btm d-flex align-items-center justify-content-between\">\r\n                                                                                                                                        <div class=\"btn-part\">\r\n                                                    <a class=\"readon-arrow\" href=\"https:\/\/saera.eu\/en\/2026\/03\/17\/speech-in-noise-testing-in-arabic-a-literature-review-and-clinical-implications-for-lebanese-arabic\/\">\r\n                                                        Read More <i class=\"fa fa fa-angle-right\"><\/i>\r\n                                                    <\/a>\r\n                                                <\/div>\r\n                                                                                    <\/div>\r\n\r\n                                <\/div>                                \r\n                            \r\n                            <\/div>\r\n                                                    \r\n                    <\/div>\r\n\t\t\t\t\t\t\t\t\t\t\r\n\t\t\t\t\t<div class=\"grid-item col-lg-12  filter_audiology filter_blog filter_masters-thesis \">\r\n\r\n                                                    <div class=\"no-gutter blog-item rs-blog-grid1\">\r\n                                                           \r\n                                <div class=\"image-part\">\r\n                                    <a href=\"https:\/\/saera.eu\/en\/2026\/03\/05\/tinnitus-management-and-rehabilitation\/\">\r\n                                        <img loading=\"lazy\" decoding=\"async\" width=\"1536\" height=\"1024\" src=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/03\/Rajeev-S.-2026.-Tinnitus-Management-and-Rehabilation.-SAERA.png\" class=\"attachment-full size-full wp-post-image\" alt=\"\" srcset=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/03\/Rajeev-S.-2026.-Tinnitus-Management-and-Rehabilation.-SAERA.png 1536w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/03\/Rajeev-S.-2026.-Tinnitus-Management-and-Rehabilation.-SAERA-300x200.png 300w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/03\/Rajeev-S.-2026.-Tinnitus-Management-and-Rehabilation.-SAERA-1024x683.png 1024w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/03\/Rajeev-S.-2026.-Tinnitus-Management-and-Rehabilation.-SAERA-768x512.png 768w\" sizes=\"(max-width: 1536px) 100vw, 1536px\" \/>                                    <\/a> \r\n                                <\/div>                             \r\n                                \r\n                                <div class=\"blog-content\">                                    \r\n                                                                               <ul class=\"blog-meta\">\r\n                                                                                                                                            <li><i class=\"fa fa-calendar-check-o\"><\/i> 5 March 2026<\/li>\r\n                                                                                                                                                                                <\/ul>\r\n                                                                                \r\n                                        <h3 class=\"title dd\"><a href=\"https:\/\/saera.eu\/en\/2026\/03\/05\/tinnitus-management-and-rehabilitation\/\">Tinnitus Management and Rehabilitation: The Efficiency of Tinnitus Masker and Cognitive Behavioral Therapy in Patients with Normal Hearing and Mild to Moderate Hearing Loss<\/a><\/h3>\r\n                                                                                <div class=\"btn-btm d-flex align-items-center justify-content-between\">\r\n                                                                                                                                        <div class=\"btn-part\">\r\n                                                    <a class=\"readon-arrow\" href=\"https:\/\/saera.eu\/en\/2026\/03\/05\/tinnitus-management-and-rehabilitation\/\">\r\n                                                        Read More <i class=\"fa fa fa-angle-right\"><\/i>\r\n                                                    <\/a>\r\n                                                <\/div>\r\n                                                                                    <\/div>\r\n\r\n                                <\/div>                                \r\n                            \r\n                            <\/div>\r\n                                                    \r\n                    <\/div>\r\n\t\t\t\t\t\t\t\t\t\t\r\n\t\t\t\t\t<div class=\"grid-item col-lg-12  filter_audiology filter_blog filter_masters-thesis \">\r\n\r\n                                                    <div class=\"no-gutter blog-item rs-blog-grid1\">\r\n                                                           \r\n                                <div class=\"image-part\">\r\n                                    <a href=\"https:\/\/saera.eu\/en\/2026\/02\/17\/comparative-sound-processing-strategies-in-cochlear-implants\/\">\r\n                                        <img loading=\"lazy\" decoding=\"async\" width=\"1536\" height=\"1024\" src=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/02\/Khalil-E.-M.-2026.-Comparative-Sound-Processing-Strategies-in-Cochlear-Implants-Cochlear-ACE-MED-EL-FS4-and-Advanced-Bionics-HiResOptima.-SAERA.png\" class=\"attachment-full size-full wp-post-image\" alt=\"\" srcset=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/02\/Khalil-E.-M.-2026.-Comparative-Sound-Processing-Strategies-in-Cochlear-Implants-Cochlear-ACE-MED-EL-FS4-and-Advanced-Bionics-HiResOptima.-SAERA.png 1536w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/02\/Khalil-E.-M.-2026.-Comparative-Sound-Processing-Strategies-in-Cochlear-Implants-Cochlear-ACE-MED-EL-FS4-and-Advanced-Bionics-HiResOptima.-SAERA-300x200.png 300w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/02\/Khalil-E.-M.-2026.-Comparative-Sound-Processing-Strategies-in-Cochlear-Implants-Cochlear-ACE-MED-EL-FS4-and-Advanced-Bionics-HiResOptima.-SAERA-1024x683.png 1024w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/02\/Khalil-E.-M.-2026.-Comparative-Sound-Processing-Strategies-in-Cochlear-Implants-Cochlear-ACE-MED-EL-FS4-and-Advanced-Bionics-HiResOptima.-SAERA-768x512.png 768w\" sizes=\"(max-width: 1536px) 100vw, 1536px\" \/>                                    <\/a> \r\n                                <\/div>                             \r\n                                \r\n                                <div class=\"blog-content\">                                    \r\n                                                                               <ul class=\"blog-meta\">\r\n                                                                                                                                            <li><i class=\"fa fa-calendar-check-o\"><\/i> 17 February 2026<\/li>\r\n                                                                                                                                                                                <\/ul>\r\n                                                                                \r\n                                        <h3 class=\"title dd\"><a href=\"https:\/\/saera.eu\/en\/2026\/02\/17\/comparative-sound-processing-strategies-in-cochlear-implants\/\">Comparative Sound-Processing Strategies in Cochlear Implants: Cochlear (ACE), MED-EL (FS4), and Advanced Bionics (HiRes\/Optima)<\/a><\/h3>\r\n                                                                                <div class=\"btn-btm d-flex align-items-center justify-content-between\">\r\n                                                                                                                                        <div class=\"btn-part\">\r\n                                                    <a class=\"readon-arrow\" href=\"https:\/\/saera.eu\/en\/2026\/02\/17\/comparative-sound-processing-strategies-in-cochlear-implants\/\">\r\n                                                        Read More <i class=\"fa fa fa-angle-right\"><\/i>\r\n                                                    <\/a>\r\n                                                <\/div>\r\n                                                                                    <\/div>\r\n\r\n                                <\/div>                                \r\n                            \r\n                            <\/div>\r\n                                                    \r\n                    <\/div>\r\n\t\t\t\t\t\t\t\t\t\t\r\n\t\t\t\t\t<div class=\"grid-item col-lg-12  filter_collaborations \">\r\n\r\n                                                    <div class=\"no-gutter blog-item rs-blog-grid1\">\r\n                                                           \r\n                                <div class=\"image-part\">\r\n                                    <a href=\"https:\/\/saera.eu\/en\/2026\/02\/11\/saera-contributes-standardised-assessment-tools-to-ricpp-testing-laboratory\/\">\r\n                                        <img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"685\" src=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/02\/WhatsApp-Image-2026-02-11-at-11.45.17-e1770815562912.jpeg\" class=\"attachment-full size-full wp-post-image\" alt=\"\" srcset=\"https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/02\/WhatsApp-Image-2026-02-11-at-11.45.17-e1770815562912.jpeg 1200w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/02\/WhatsApp-Image-2026-02-11-at-11.45.17-e1770815562912-300x171.jpeg 300w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/02\/WhatsApp-Image-2026-02-11-at-11.45.17-e1770815562912-1024x585.jpeg 1024w, https:\/\/saera.eu\/en\/wp-content\/uploads\/2026\/02\/WhatsApp-Image-2026-02-11-at-11.45.17-e1770815562912-768x438.jpeg 768w\" sizes=\"(max-width: 1200px) 100vw, 1200px\" \/>                                    <\/a> \r\n                                <\/div>                             \r\n                                \r\n                                <div class=\"blog-content\">                                    \r\n                                                                               <ul class=\"blog-meta\">\r\n                                                                                                                                            <li><i class=\"fa fa-calendar-check-o\"><\/i> 11 February 2026<\/li>\r\n                                                                                                                                                                                <\/ul>\r\n                                                                                \r\n                                        <h3 class=\"title dd\"><a href=\"https:\/\/saera.eu\/en\/2026\/02\/11\/saera-contributes-standardised-assessment-tools-to-ricpp-testing-laboratory\/\">SAERA Contributes Standardised Assessment Tools to RICPP Testing Laboratory<\/a><\/h3>\r\n                                                                                <div class=\"btn-btm d-flex align-items-center justify-content-between\">\r\n                                                                                                                                        <div class=\"btn-part\">\r\n                                                    <a class=\"readon-arrow\" href=\"https:\/\/saera.eu\/en\/2026\/02\/11\/saera-contributes-standardised-assessment-tools-to-ricpp-testing-laboratory\/\">\r\n                                                        Read More <i class=\"fa fa fa-angle-right\"><\/i>\r\n                                                    <\/a>\r\n                                                <\/div>\r\n                                                                                    <\/div>\r\n\r\n                                <\/div>                                \r\n                            \r\n                            <\/div>\r\n                                                    \r\n                    <\/div>\r\n\t\t\t\t\t                 \r\n                         \r\n                <\/div>   \r\n                               \r\n            \t    \r\n                              \r\n\t\t<\/div>\r\n\t   \t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Report on the journal article of Prasad et al. (2021) &#8220;Brain Disease Network Analysis to Elucidate the Neurological Manifestations of COVID-19&#8221;, by Francia de los Reyes.<\/p>\n","protected":false},"author":1,"featured_media":15058,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"elementor_header_footer","format":"standard","meta":{"footnotes":""},"categories":[91,176,92],"tags":[126,104],"class_list":["post-15057","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles","category-blog","category-neuroscience","tag-covid-19","tag-neuroscience"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Brain Disease Network Analysis: COVID-19 Neurological Effects<\/title>\n<meta name=\"description\" content=\"Explore the neurological manifestations of COVID-19 through brain disease network analysis. 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